Description

2(3H)-Furanone,4-Ethyldihydro-3,4-Dimethyl-5-Phenyl-,(3R,4R,5R)-Rel-(9Ci) is a high-purity, stereochemically defined chiral lactone building block of significant interest in advanced organic synthesis. Its precise three-dimensional structure makes it a valuable precursor for the development of complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and process chemists in fine chemical, agrochemical, and fragrance industries seeking to introduce specific stereocenters and functional complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring specific stereochemistry for efficacy.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where the spatial arrangement of the molecule is critical for biological activity.
• Flavor & Fragrance Chemistry: Serves as a building block for creating complex, naturally-derived aroma compounds and flavorants with specific olfactory profiles.
• Asymmetric Catalysis Ligand Precursor: Can be utilized in the synthesis of novel chiral ligands or organocatalysts for stereoselective transformations.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers with potential advanced optical or mechanical properties.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	2(3H)-Furanone,4-Ethyldihydro-3,4-Dimethyl-5-Phenyl-,(3R,4R,5R)-Rel-(9Ci)
CAS No.	732302-44-2
Molecular Formula	C14H18O2
Molecular Weight	218.29 g/mol
Synonyms	(3R,4R,5R)-4-Ethyl-3,4-dimethyl-5-phenyltetrahydrofuran-2-one; 4-Ethyldihydro-3,4-dimethyl-5-phenyl-2(3H)-furanone, (3R,4R,5R)-rel-; rel-(3R,4R,5R)-4-Ethyl-3,4-dimethyl-5-phenyltetrahydrofuran-2-one; Tetrahydro-2(3H)-furanone, 4-ethyldihydro-3,4-dimethyl-5-phenyl-, (3R,4R,5R)-rel-; Chiral γ-lactone derivative; 4-Ethyl-3,4-dimethyl-5-phenyl-dihydro-2(3H)-furanone
EINECS	Contact for details

Quality Control

Our 2(3H)-Furanone,4-Ethyldihydro-3,4-Dimethyl-5-Phenyl-,(3R,4R,5R)-Rel-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/Chiral GC), identity confirmation (IR, NMR), and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC/GC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.