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(1R,2R)-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid CAS NO 731811-50-0


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CAS No.:731811-50-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1R,2R)-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid is a high-purity chiral cyclopropane derivative, a critical building block in modern asymmetric synthesis. Its rigid, three-membered ring fused with a pyridine moiety makes it a valuable scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and advanced intermediates.

Application

  • Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drugs.
  • Agrochemical Synthesis: Used in the development of novel herbicides and insecticides, where the cyclopropane ring contributes to biological activity and stability.
  • Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric catalysis.
  • Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular probe.
  • Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or mechanical properties.
  • Academic & Industrial R&D: A versatile building block for exploratory synthetic chemistry in both academic and industrial research laboratories.

Basic Information

Product Name (1R,2R)-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid
CAS No. 731811-50-0
Molecular Formula C9H9NO2
Molecular Weight 163.17 g/mol
Synonyms (1R,2R)-2-(3-Pyridyl)cyclopropanecarboxylic Acid; (1R,2R)-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid; (1R,2R)-2-(3-Pyridinyl)cyclopropanecarboxylic Acid; (1R,2R)-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid; (1R,2R)-2-(3-Pyridyl)cyclopropane-1-carboxylic Acid; (1R,2R)-rel-2-(3-Pyridinyl)cyclopropanecarboxylic Acid; (1R,2R)-2-(3-Pyridyl)cyclopropanecarboxylate
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Quality Control

Our (1R,2R)-2-(Pyridin-3-Yl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure identity, purity, and enantiomeric excess meet the highest standards. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as oxidizing agents and bases.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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