Description

3-Pyridinecarboxamide,n-(2,3-Dihydro-1H-Inden-5-Yl)-1,6-Dihydro-6-Oxo-(9Ci) is a high-purity, advanced pharmaceutical intermediate belonging to a class of nitrogen-containing heterocyclic compounds. This compound is of significant commercial interest for its role in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique pyridine-indane hybrid structure.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic & Institutional Research: Utilized in universities and research institutes for exploring new chemical entities and reaction methodologies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	3-Pyridinecarboxamide,n-(2,3-Dihydro-1H-Inden-5-Yl)-1,6-Dihydro-6-Oxo-(9Ci)
CAS No.	731778-01-1
Molecular Formula	C15H14N2O2
Molecular Weight	254.29 g/mol
Synonyms	N-(2,3-Dihydro-1H-inden-5-yl)-1,6-dihydro-6-oxopyridine-3-carboxamide; 5-Carbamoyl-2-pyridone derivative; 6-Oxo-1,6-dihydropyridine-3-carboxamide, N-(2,3-dihydro-1H-inden-5-yl)-; (9CI) 731778-01-1; Indanyl pyridone carboxamide; Potential pharmaceutical intermediate 731778-01-1
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and development work. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We implement HPLC, GC, NMR, and MS for thorough characterization, ensuring the material meets the exacting standards required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The material may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.