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Carbamic Acid, (2-Amino-3,4,5,6-Tetrahydro-3-Pyridinyl)-, 1,1-Dimethylethyl CAS NO 731763-67-0


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CAS No.:731763-67-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Carbamic Acid, (2-Amino-3,4,5,6-Tetrahydro-3-Pyridinyl)-, 1,1-Dimethylethyl Ester is a protected amino acid derivative featuring a carbamate (Boc) group and a partially saturated pyridine ring, serving as a critical synthetic intermediate. Its primary value lies in enabling the controlled synthesis and modification of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable building blocks for drug discovery programs.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular disorders.
  • Peptidomimetic Research: Used in the design and construction of peptide analogs and conformationally restricted scaffolds for drug discovery.
  • Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amines in multi-step synthetic sequences.
  • Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
  • Ligand and Catalyst Development: Precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
  • Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name Carbamic Acid, (2-Amino-3,4,5,6-Tetrahydro-3-Pyridinyl)-, 1,1-Dimethylethyl Ester
CAS No. 731763-67-0
Molecular Formula C10H20N2O2
Molecular Weight 200.28 g/mol
Synonyms N-Boc-2-Amino-3,4,5,6-tetrahydropyridine; 2-((tert-Butoxycarbonyl)amino)-3,4,5,6-tetrahydropyridine; tert-Butyl (2-amino-3,4,5,6-tetrahydro-3-pyridinyl)carbamate; Boc-2-Amino-3,4,5,6-tetrahydropyridine; 2-Amino-N-Boc-3,4,5,6-tetrahydropyridine; (2-Amino-1,4,5,6-tetrahydropyridin-3-yl)carbamic acid tert-butyl ester; 731763-67-0; tert-Butyl N-(2-amino-3,4,5,6-tetrahydropyridin-3-yl)carbamate
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Quality Control

Our Carbamic Acid, (2-Amino-3,4,5,6-Tetrahydro-3-Pyridinyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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