Description

Methyl-3-Isocyano-3-(2-Fluorophenyl)Propionate is a versatile and high-value organic building block featuring both an isocyano and an ester functional group. This compound is critical for the synthesis of complex heterocycles and peptidomimetics, enabling advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Agrochemical Research: Used in the development of new active ingredients for crop protection with potential herbicidal or insecticidal properties.
• Peptidomimetic Synthesis: The isocyano group facilitates multicomponent reactions (like Ugi or Passerini) to create peptide-like structures with enhanced metabolic stability.
• Heterocycle Construction: Serves as a versatile reagent for the preparation of five- and six-membered nitrogen-containing heterocycles, such as oxazoles and imidazoles.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with unique properties.

Basic Information

Product Name	Methyl-3-Isocyano-3-(2-Fluorophenyl)Propionate
CAS No.	730971-55-8
Molecular Formula	C11H10FNO2
Molecular Weight	207.20 g/mol
Synonyms	Methyl 3-Isocyano-3-(2-fluorophenyl)propanoate; 3-Isocyano-3-(2-fluorophenyl)propionic Acid Methyl Ester; 2-Fluorophenyl Isocyanoacetate Methyl Ester Derivative; Methyl (2-Fluorophenyl)isocyanoacetate; Propanoic acid, 3-isocyano-3-(2-fluorophenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl-3-Isocyano-3-(2-Fluorophenyl)Propionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.