Description

Methyl 3-Isocyano-3-(3-Fluorophenyl)Propionate is a versatile and high-value organic building block featuring both an isocyano and an ester functional group. This compound is critical for the synthesis of complex heterocycles and peptidomimetics, enabling advanced medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs) and agrochemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nitrogen-containing heterocycles, such as oxazoles and imidazoles, which are core structures in many drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the reactivity of the isocyano group to introduce complex side chains.
• Peptidomimetics Research: Serves as a crucial building block for creating non-peptide compounds that mimic the structure and function of peptides, useful in drug discovery.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with unique properties.
• Catalyst Ligand Synthesis: Employed in the preparation of novel chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Utilized to create isonitrile-containing probes for studying biological processes and protein interactions.

Basic Information

Product Name	Methyl 3-Isocyano-3-(3-Fluorophenyl)Propionate
CAS No.	730971-50-3
Molecular Formula	C11H10FNO2
Molecular Weight	207.20 g/mol
Synonyms	Methyl 3-Isocyano-3-(3-fluorophenyl)propanoate; 3-Fluorophenyl Isocyanoacetate Methyl Ester; 3-Isocyano-3-(3-fluorophenyl)propionic Acid Methyl Ester; Methyl (3-Fluorophenyl)isocyanoacetate; Methyl 3-(3-Fluorophenyl)-3-isocyanopropionate; 730971-50-3; Propanoic acid, 3-isocyano-3-(3-fluorophenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Isocyano-3-(3-Fluorophenyl)Propionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.