Description

2,6-Dibromo-4-Methylisocyanide is a halogenated isocyanide building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the construction of complex heterocycles and functional materials, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for applications such as palladium-catalyzed cross-coupling reactions and the synthesis of novel ligands.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex molecular architectures.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection products.
• Material Science: Serves as a precursor for the development of specialized polymers, ligands for catalysis, and functional organic materials.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions, such as Sonogashira, Suzuki-Miyaura, and Buchwald-Hartwig aminations, to introduce the isocyanide functional group.
• Ligand Synthesis: Utilized for the preparation of novel isocyanide-based ligands used in homogeneous catalysis.
• Chemical Research: A valuable reagent in academic and industrial laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	2,6-Dibromo-4-Methylisocyanide
CAS No.	730971-40-1
Molecular Formula	C8H5Br2N
Molecular Weight	274.94 g/mol
Synonyms	4-Methyl-2,6-dibromophenyl isocyanide; 2,6-Dibromo-4-methylphenyl isocyanide; 1-Isocyano-2,6-dibromo-4-methylbenzene; 2,6-Dibromo-p-tolyl isocyanide; Isocyanic acid, 2,6-dibromo-4-methylphenyl ester; (2,6-Dibromo-4-methylphenyl)isocyanide
EINECS	Contact for details

Quality Control

Our 2,6-Dibromo-4-Methylisocyanide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.