Description

Methyl-3-Isocyano-2-Methylbenzoate is a versatile isocyanide derivative, a crucial building block in organic synthesis. This compound matters for its high reactivity, enabling the efficient construction of complex heterocyclic frameworks and natural product analogs. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediates: A key synthon in the synthesis of complex drug candidates, particularly for nitrogen-containing heterocycles.
• Agrochemical Research: Used in the development of novel pesticides and herbicides through multi-component reactions.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic materials.
• Academic & R&D Laboratories: Employed in methodological studies, such as Ugi and Passerini multi-component reactions, for library synthesis.
• Peptidomimetics: Facilitates the creation of peptide analogs and constrained structures in medicinal chemistry programs.
• Catalyst Ligand Synthesis: Used to prepare specialized isocyanide-based ligands for transition metal catalysis.

Basic Information

Product Name	Methyl-3-Isocyano-2-Methylbenzoate
CAS No.	730971-38-7
Molecular Formula	C11H11NO2
Molecular Weight	189.21 g/mol
Synonyms	3-Isocyano-2-methylbenzoic acid methyl ester; Methyl 3-isocyano-2-methylbenzoate; 2-Methyl-3-isocyanobenzoic acid methyl ester; Benzoic acid, 3-isocyano-2-methyl-, methyl ester; Methyl 2-methyl-3-isocyanobenzoate
EINECS	Contact for details

Quality Control

Our Methyl-3-Isocyano-2-Methylbenzoate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from research to commercial scale, ensuring reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.