Description

4-Bromo-2-Fluorophenylisocyanide is a versatile aromatic isocyanide building block, a key intermediate in modern synthetic chemistry. Its value lies in its dual functionality, where the isocyanide group enables multicomponent reactions and the halogen substituents provide sites for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactive molecule creation.
• Material Science: Serves as a precursor for functional polymers, ligands for catalysis, and metal-organic frameworks (MOFs).
• Academic & R&D: A valuable reagent in organic synthesis laboratories for exploring new multicomponent reactions (MCRs) like the Ugi and Passerini reactions.
• Chemical Biology: Employed in the development of chemical probes and bioconjugation tools due to the reactive isocyanide moiety.

Basic Information

Product Name	4-Bromo-2-Fluorophenylisocyanide
CAS No.	730964-93-9
Molecular Formula	C7H3BrFN
Molecular Weight	200.01 g/mol
Synonyms	2-Fluoro-4-bromophenyl isocyanide; 1-Bromo-3-fluoro-4-isocyanobenzene; 4-Bromo-2-fluorobenzene isocyanide; 4-Bromo-2-fluorophenyl isonitrile; Isocyanide, (4-bromo-2-fluorophenyl)-; (4-Bromo-2-fluorophenyl)isocyanide
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorophenylisocyanide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.