Description

2-Isocyano-2'-Fluoro-5-Bromobenzophenone is a specialized, high-value organic building block featuring a unique combination of reactive functional groups. This compound is critical for the synthesis of complex heterocyclic scaffolds and advanced pharmaceutical intermediates. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing benzodiazepine or related heterocyclic cores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and isocyano groups for structural diversity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for organic electronic materials and photoactive polymers due to its conjugated benzophenone structure.
• Chemical Biology Probes: Utilized in the development of activity-based probes and bioconjugation reagents, where the isocyano group enables specific labeling.

Basic Information

Product Name	2-Isocyano-2'-Fluoro-5-Bromobenzophenone
CAS No.	730964-92-8
Molecular Formula	C14H7BrFNO
Molecular Weight	304.12 g/mol
Synonyms	2-Isocyanato-2'-Fluoro-5-Bromobenzophenone (common misnomer); 2'-Fluoro-5-bromo-2-isocyanobenzophenone; (2-Isocyanophenyl)(2-fluoro-5-bromophenyl)methanone; 730964-92-8; Benzophenone, 2-isocyano-2'-fluoro-5-bromo-; 5-Bromo-2'-fluoro-2-isocyanobenzophenone
EINECS	Contact for details

Quality Control

Our 2-Isocyano-2'-Fluoro-5-Bromobenzophenone is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive R&D and scale-up processes. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.