Description

2-Isocyano-5-Chloro-2'-Fluorobenzophenone is a high-purity, specialized organic intermediate featuring a reactive isocyano group and halogenated aromatic system. This compound is critical for the synthesis of complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs) where precise molecular architecture is required. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry research for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, leveraging its halogenated benzophenone core for bioactivity.
• Organic Ligand Precursor: Serves as a precursor for isocyanide-based ligands used in organometallic chemistry and catalysis.
• Material Science Research: Employed in the creation of specialized polymers and functional materials that require halogen and isocyano functional groups.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological processes due to its reactive handle for bioconjugation.

Basic Information

Product Name	2-Isocyano-5-Chloro-2'-Fluorobenzophenone
CAS No.	730964-91-7
Molecular Formula	C14H7ClFNO
Molecular Weight	259.66 g/mol
Synonyms	5-Chloro-2'-fluoro-2-isocyanobenzophenone; 2-Isocyanato-5-chloro-2'-fluorobenzophenone (common misnomer); 2-Isocyano-5-chloro-2'-fluorodiphenyl ketone; Benzophenone, 2-isocyano-5-chloro-2'-fluoro-; (2-Isocyanophenyl)(5-chloro-2-fluorophenyl)methanone; CAS 730964-91-7
EINECS	Contact for details

Quality Control

Our 2-Isocyano-5-Chloro-2'-Fluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maximize stability, as the isocyano group can be sensitive.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.