Description

D,L-3-Isocyano-n-Butyric Acid Methyl Ester is a versatile chiral building block and isocyanide reagent used in multicomponent reactions and peptide synthesis. This compound is critical for the efficient construction of complex heterocycles and peptidomimetics, enabling the discovery and development of novel pharmaceuticals. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, combinatorial chemistry, and agrochemical research.

Application

• Medicinal Chemistry & Drug Discovery: A key reagent in Passerini and Ugi multicomponent reactions for the rapid synthesis of diverse compound libraries.
• Peptide & Peptidomimetic Synthesis: Serves as an isocyanide component for the preparation of pseudopeptides and conformationally constrained analogs.
• Agrochemical Research: Used in the synthesis of novel active ingredients with potential herbicidal or insecticidal properties.
• Material Science: Employed in the development of functional polymers and smart materials via isocyanide-based polymerization.
• Academic & Process R&D: A valuable tool for methodology development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	D,L-3-Isocyano-n-Butyric Acid Methyl Ester
CAS No.	730964-86-0
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	Methyl 3-Isocyanobutanoate; Methyl DL-3-Isocyanobutyrate; 3-Isocyanobutyric Acid Methyl Ester; Methyl 3-Isocyanobutyrate; Butanoic acid, 3-isocyano-, methyl ester; DL-3-Isocyanobutyric Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our D,L-3-Isocyano-n-Butyric Acid Methyl Ester is produced under strict quality management protocols. Each batch is analyzed to ensure high chemical purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and light-sensitive nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent moisture uptake. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.