Description

2-Isocyanosuccinic Acid Dimethyl Ester is a versatile and reactive chemical intermediate, primarily valued for its isocyanate functionality and ester groups. This compound is crucial for synthesizing complex molecules, including heterocyclic compounds and active pharmaceutical ingredients (APIs), due to its ability to participate in cycloaddition and condensation reactions. It is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those containing heterocyclic cores like imidazolidines or hydantoins.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its reactive sites allow for the introduction of specific bioactive moieties.
• Polymer Modification: Serves as a cross-linking agent or a monomer for producing specialty polyurethanes and polyamides with tailored properties.
• Chemical Research (R&D): Employed in academic and industrial laboratories for developing new synthetic methodologies and exploring [2+2] or [4+2] cycloaddition reactions.
• Peptide Mimetics: Useful in medicinal chemistry for creating constrained peptide analogs and protease inhibitors.
• Dye and Pigment Intermediate: Acts as a precursor in the synthesis of complex organic colorants.

Basic Information

Product Name	2-Isocyanosuccinic Acid Dimethyl Ester
CAS No.	730964-72-4
Molecular Formula	C7H9NO5
Molecular Weight	187.15 g/mol
Synonyms	Dimethyl 2-isocyanatosuccinate; Succinic acid, 2-isocyanato-, dimethyl ester; 2-Isocyanato-dimethyl succinate; Dimethyl 2-isocyanobutanedioate; 2-Isocyanato-butanedioic acid dimethyl ester; NSC 760963; AI3-52311
EINECS	Contact for details

Quality Control

Our 2-Isocyanosuccinic Acid Dimethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.