Description

2-(4-Bromophenyl)Ethylisocyanide is a specialized organic building block featuring both an aryl bromide and an isocyanide functional group. This unique bifunctional structure makes it a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical and advanced materials research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as multicomponent reactions and heterocycle synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those requiring complex heterocyclic cores via Passerini or Ugi multicomponent reactions.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging the reactivity of the isocyanide group.
• Ligand Synthesis: Serves as a building block for creating specialized ligands used in catalysis and material science.
• Polymer & Material Science: Incorporated into specialty monomers for producing polymers with unique properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes and other tools for studying biological systems.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	2-(4-Bromophenyl)Ethylisocyanide
CAS No.	730964-66-6
Molecular Formula	C9H8BrN
Molecular Weight	210.07 g/mol
Synonyms	1-(4-Bromophenyl)-2-isocyanoethane; 2-(4-Bromophenyl)ethyl isocyanide; 4-Bromophenethyl isocyanide; 2-(p-Bromophenyl)ethyl isocyanide; (4-Bromophenethyl) isocyanide; 2-(4-Bromophenyl)ethanamine, N-isocyano-; Isocyanomethyl-(4-bromophenyl)methane; 730964-66-6
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)Ethylisocyanide is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with your specifications. For custom synthesis or specific purity requirements (e.g., >97%, >98%), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the light-sensitive nature of this compound, containers should be amber glass or opaque. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.