Description

2-(3-Chlorophenyl)Ethylisocyanide is a specialized organic building block featuring an isocyanide functional group attached to a chlorinated phenyl ring. This compound is valued for its versatility as a key intermediate in multi-component reactions and metal-catalyzed transformations, enabling the efficient synthesis of complex heterocyclic and functionalized molecular architectures. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel bioactive compounds and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly for constructing heterocyclic cores prevalent in medicinal chemistry.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its reactivity to create new active ingredients.
• Ligand Synthesis: Serves as a starting material for preparing specialized isocyanide-based ligands used in catalysis and material science.
• Multi-Component Reactions (MCRs): Employed in Passerini and Ugi-type reactions for the rapid generation of chemical diversity and compound libraries.
• Polymer & Material Science: Incorporated into monomers for creating functional polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying biological processes.

Basic Information

Product Name	2-(3-Chlorophenyl)Ethylisocyanide
CAS No.	730964-64-4
Molecular Formula	C9H8ClN
Molecular Weight	165.62 g/mol
Synonyms	1-Chloro-3-(2-isocyanoethyl)benzene; 2-(3-Chlorophenyl)ethyl isocyanide; 3-Chlorophenethyl isocyanide; (3-Chlorophenyl)ethyl isonitrile; 2-(3-Chlorophenyl)ethanyl isocyanide; Isocyano(3-chlorophenylethane); 730964-64-4
EINECS	Contact for details

Quality Control

Our 2-(3-Chlorophenyl)Ethylisocyanide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizers and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.