Description

3-Fluorophenethylisocyanide is a specialized organic building block featuring both an isocyanide functional group and a fluorinated aromatic ring. This unique structure makes it a valuable intermediate for the synthesis of complex heterocycles and bioactive molecules in medicinal chemistry. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for lead optimization and the discovery of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nitrogen-containing heterocycles, such as imidazoles and oxazoles, for drug discovery programs.
• Agrochemical Research: Used in the development of novel fungicides and herbicides, leveraging the bioactivity of the isocyanide moiety.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Chemical Biology: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents due to its reactive isocyanide group.
• Catalyst Ligand Synthesis: Used to create novel ligands for transition metal catalysts used in asymmetric synthesis.
• Academic & Contract Research: A versatile reagent for methodological development in organic synthesis and multi-component reactions (MCRs).

Basic Information

Product Name	3-Fluorophenethylisocyanide
CAS No.	730964-63-3
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	1-Isocyano-2-(3-fluorophenyl)ethane; 2-(3-Fluorophenyl)ethyl isocyanide; 3-Fluorophenethyl isonitrile; (3-Fluorophenyl)ethyl isocyanide; m-Fluorophenethyl isocyanide; 3-Fluorobenzeneethanamine, N-formyl-, nitrile; 730964-63-3; 3-Fluorophenethyl isocyanide
EINECS	Contact for details

Quality Control

Our 3-Fluorophenethylisocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, and well-ventilated place. Due to its highly volatile and easily oxidized nature, minimize exposure to air, moisture, and elevated temperatures. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.