Description

2-Fluorophenethylisocyanide is a specialized organic building block featuring both an isocyanide functional group and a fluorinated aromatic ring. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex heterocycles and bioactive molecules in medicinal chemistry and materials science. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for creating diverse heterocyclic libraries via multicomponent reactions (MCRs) like the Ugi and Passerini reactions.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for isocyanide-based ligands used in catalysis and coordination chemistry.
• Material Science: Employed in the research and development of functional polymers and advanced organic materials.
• Chemical Biology Probes: Useful for creating activity-based probes and other tools for studying biological processes.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	2-Fluorophenethylisocyanide
CAS No.	730964-62-2
Molecular Formula	C9H8FN
Molecular Weight	149.17 g/mol
Synonyms	1-Isocyano-2-(2-fluorophenyl)ethane; 2-(2-Fluorophenyl)ethyl isocyanide; (2-Fluorophenethyl)isocyanide; 2-Fluorophenethyl isonitrile; 2-Fluorophenethyl Isocyanide; 2-Fluorobenzeneethanamine, N-methylene-; 730964-62-2
EINECS	Contact for details

Quality Control

Our 2-Fluorophenethylisocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place at 2-8°C or as specified on the label. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.