Description

2-Methylphenethylisocyanide is a specialized organic building block featuring a reactive isocyanide functional group. This compound is valued for its versatility in multi-component reactions, enabling the efficient synthesis of complex heterocyclic scaffolds and natural product analogs. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for lead discovery and optimization.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in the construction of nitrogen-containing heterocycles via Passerini and Ugi reactions.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its ability to introduce diverse molecular complexity.
• Chemical Biology Probe Synthesis: Employed in the creation of isocyanide-containing probes for studying biological pathways and protein interactions.
• Material Science: Serves as a monomer or precursor in the development of functional polymers and smart materials with tailored properties.
• Academic & Industrial R&D: A fundamental reagent in methodological organic chemistry research for developing new catalytic and synthetic transformations.

Basic Information

Product Name	2-Methylphenethylisocyanide
CAS No.	730964-61-1
Molecular Formula	C10H11N
Molecular Weight	145.20 g/mol
Synonyms	1-Isocyano-2-(2-methylphenyl)ethane; (2-Methylphenethyl)isocyanide; 2-(2-Methylphenyl)ethyl isocyanide; 2-Methylphenethyl isonitrile; o-Methylphenethylisocyanide; 2-(o-Tolyl)ethyl isocyanide; α-Tolylisocyanide (related); Isocyanomethylbenzene derivative
EINECS	Contact for details

Quality Control

Our 2-Methylphenethylisocyanide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and handled in a fume hood to minimize exposure and prevent loss of material.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.