Description

3-Methylphenethylisocyanide is a specialized organic building block featuring a reactive isocyanide functional group. This compound is valued for its role in facilitating the synthesis of complex heterocyclic and peptidomimetic structures through multicomponent reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for lead optimization and the discovery of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of drug candidates, particularly for constructing heterocyclic cores via Ugi, Passerini, and related multicomponent reactions.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides by enabling the efficient assembly of diverse chemical scaffolds.
• Chemical Biology & Probe Development: Used to create isocyanide-containing probes for studying biological pathways and protein interactions.
• Material Science: Serves as a building block for novel polymers and functional materials with tailored properties.
• Academic & Contract Research: Essential for methodological development in organic synthesis and for producing custom libraries of compounds for screening.

Basic Information

Product Name	3-Methylphenethylisocyanide
CAS No.	730964-60-0
Molecular Formula	C10H11N
Molecular Weight	145.20 g/mol
Synonyms	1-Isocyano-2-(3-methylphenyl)ethane; 2-(3-Methylphenyl)ethyl isocyanide; m-Methylphenethyl isocyanide; 3-Methylbenzeneethanamine, N-(methylidyne)-; (3-Methylphenethyl)isocyanide; Isocyanomethane, (3-methylphenethyl)-; 730964-60-0
EINECS	Contact for details

Quality Control

Our 3-Methylphenethylisocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.