Description

2,4-Dichlorobenzylisocyanide is a versatile and reactive organic building block, specifically an isocyanide derivative. Its value lies in its role as a critical precursor in multi-component reactions, such as the Ugi and Passerini reactions, enabling the efficient synthesis of complex heterocycles and pharmacophores. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create novel molecular libraries and functional materials.

Application

• Pharmaceutical Intermediate: A key reactant in the synthesis of diverse drug candidates and bioactive molecules through isocyanide-based multicomponent reactions (IMCRs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by constructing novel heterocyclic scaffolds.
• Material Science: Serves as a building block for creating functional polymers, ligands for catalysis, and advanced organic frameworks.
• Chemical Synthesis: Employed in organic methodology development for constructing complex amides, peptides, and nitrogen-containing heterocycles.
• Academic & Industrial R&D: A valuable reagent for discovery chemistry in both university laboratories and corporate research facilities.

Basic Information

Product Name	2,4-Dichlorobenzylisocyanide
CAS No.	730964-58-6
Molecular Formula	C8H5Cl2N
Molecular Weight	186.04 g/mol
Synonyms	1-Isocyano-2,4-dichlorobenzene; (2,4-Dichlorophenyl)methyl isocyanide; 2,4-Dichlorobenzyl isonitrile; 2,4-Dichlorobenzyl Isocyanide; α-Isocyano-2,4-dichlorotoluene; 2,4-Dichloro-α-isocyanotoluene; 2,4-Dichlorobenzyl Isonitrile
EINECS	Contact for details

Quality Control

Our 2,4-Dichlorobenzylisocyanide is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat and ignition sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.