Description

(3R)-3-Methyl-4-(tert-Buty)Diphenylsilyloxy)Pent-1-Ene is a chiral, protected allylic alcohol intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a versatile building block for constructing complex molecules with defined stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other high-value chiral targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized in stereoselective reactions, including cross-couplings and nucleophilic additions, to install complex molecular architectures.
• Natural Product Synthesis: Serves as a building block in the total synthesis of complex natural products requiring specific (R)-configured stereocenters.
• Ligand and Catalyst Development: Used as a precursor for developing new chiral ligands and organocatalysts for enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and flavors & fragrances where high purity and specific chirality are critical.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in laboratory-scale and process chemistry.

Basic Information

Product Name	(3R)-3-Methyl-4-(tert-Buty)Diphenylsilyloxy)Pent-1-Ene
CAS No.	730964-36-0
Molecular Formula	C22H30OSi
Molecular Weight	338.56 g/mol
Synonyms	(R)-3-Methyl-4-((tert-butyldiphenylsilyl)oxy)pent-1-ene; 1-Pentene, 3-methyl-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-, (3R)-; (3R)-3-Methyl-4-[(tert-butyldiphenylsilyl)oxy]-1-pentene; TBDPS-protected (R)-3-Methyl-4-hydroxypent-1-ene; (R)-TBDPS-O-3-Methylpent-4-en-1-ol (protected form); Chiral TBDPS ether of 3-methylpent-4-ene-1-ol
EINECS	Contact for details

Quality Control

Our (3R)-3-Methyl-4-(tert-Buty)Diphenylsilyloxy)Pent-1-Ene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC/GC), to ensure compliance with exacting standards for synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from strong acids and incompatible materials. For long-term storage, consider refrigeration at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.