Description

Methyl 2-Methoxy-5-(Trifluoromethyl)Nicotinate is a high-purity trifluoromethyl-substituted nicotinate ester, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique chemical structure, which introduces both methoxy and trifluoromethyl functionalities to create novel molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and specialty intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 2-Methoxy-5-(Trifluoromethyl)Nicotinate
CAS No.	729589-73-5
Molecular Formula	C9H8F3NO3
Molecular Weight	235.16 g/mol
Synonyms	Methyl 2-methoxy-5-(trifluoromethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-methoxy-5-(trifluoromethyl)-, methyl ester; 2-Methoxy-5-(trifluoromethyl)nicotinic acid methyl ester; Methyl 5-(trifluoromethyl)-2-methoxynicotinate; 729589-73-5; Methyl 2-methoxy-5-trifluoromethylnicotinate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Methoxy-5-(Trifluoromethyl)Nicotinate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.