Description

Spiro[4.5]Dec-7-Ene-1-Carboxaldehyde, 4,8-Dimethyl-, (4R)- (9Ci) is a high-purity, chiral spirocyclic aldehyde building block of significant interest in advanced organic synthesis. Its unique, rigid spirocyclic framework and defined stereochemistry make it a valuable precursor for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where its spiro structure can contribute to unique biological activity.
• Ligand and Catalyst Development: Employed as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: The aldehyde functional group and complex structure make it a candidate for synthesizing novel odorants and flavor molecules.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with specific thermal or optical properties.
• Academic and R&D Laboratories: A valuable tool for methodological studies in organic chemistry, including new cyclization and functionalization reactions.

Basic Information

Product Name	Spiro[4.5]Dec-7-Ene-1-Carboxaldehyde, 4,8-Dimethyl-, (4R)- (9Ci)
CAS No.	729563-50-2
Molecular Formula	C₁₃H₂₀O
Molecular Weight	192.30 g/mol
Synonyms	(4R)-4,8-Dimethylspiro[4.5]dec-7-ene-1-carboxaldehyde; (4R)-4,8-Dimethyl-1-spiro[4.5]dec-7-enecarboxaldehyde; 4,8-Dimethylspiro[4.5]dec-7-ene-1-carboxaldehyde, (4R)-; (R)-4,8-Dimethylspiro[4.5]dec-7-ene-1-carbaldehyde; Spiro[4.5]dec-7-ene-1-carboxaldehyde, 4,8-dimethyl-, (4R)-; (4R)-4,8-Dimethyl-1-azaspiro[4.5]dec-7-ene-1-carboxaldehyde (related analog); Chiral Spirocyclic Aldehyde
EINECS	Contact for details

Quality Control

Our Spiro[4.5]Dec-7-Ene-1-Carboxaldehyde, 4,8-Dimethyl-, (4R)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC/GC purity, chiral purity (enantiomeric excess), and structural confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are available for every batch and provided upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.