Description

(R)-(-)-1-Isocyanoindane is a chiral isocyanide building block of significant interest in asymmetric synthesis. This compound matters for its role as a versatile ligand and precursor in the construction of complex, stereodefined molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in catalysis and medicinal chemistry.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions.
• As a key building block for the synthesis of chiral indane-based pharmaceuticals.
• In the development of novel catalysts for enantioselective transformations.
• As a precursor for chiral isocyanide-based multicomponent reactions (MCRs).
• For research in medicinal chemistry to create stereochemically pure compound libraries.
• In the synthesis of functional materials requiring specific chirality.

Basic Information

Product Name	(R)-(-)-1-Isocyanoindane
CAS No.	728920-02-3
Molecular Formula	C10H9N
Molecular Weight	143.19 g/mol
Synonyms	(R)-1-Isocyanoindane; (R)-Indan-1-yl isocyanide; (R)-1-Isocyano-2,3-dihydro-1H-indene; (-)-1-Isocyanoindane; (R)-(-)-Indan-1-yl isocyanide; 1H-Indene, 1-isocyano-2,3-dihydro-, (1R)-
EINECS	Contact for details

Quality Control

Our (R)-(-)-1-Isocyanoindane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep container tightly sealed under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.