Description

1-[6-Chloro-2-(4-Fluoro-Phenyl)-Imidazo[1,2-A]-Pyridin-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Development: Serves as a precursor in the development and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Potential tool compound for probing biological pathways and enzyme interactions in vitro.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	1-[6-Chloro-2-(4-Fluoro-Phenyl)-Imidazo[1,2-A]-Pyridin-3-Ylmethyl]-Piperidine-4-Carboxylic Acid
CAS No.	728916-56-1
Molecular Formula	C20H19ClFN3O2
Molecular Weight	387.84 g/mol
Synonyms	1-[(6-Chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl]piperidine-4-carboxylic acid; 1-((6-Chloro-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperidine-4-carboxylic acid; 728916-56-1; UNII-9V8S8C4Q4F; 9V8S8C4Q4F; CHEMBL3185226; ZINC000003869007; SCHEMBL15406297
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and reliability for critical R&D and scale-up work. Every lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time matches reference standard
Identification (IR)	Spectrum conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.