Description

4-(5-Bromopyridin-3-Yl)-4-Hydroxybut-3-En-2-One is a high-purity brominated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a bromine substituent and a reactive enone moiety, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyridine core.
• Material Science: Building block for creating specialized ligands, catalysts, and functional organic materials.
• Chemical Synthesis: Serves as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Stille) for introducing complex molecular fragments.
• Academic & R&D: Utilized in university and corporate laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	4-(5-Bromopyridin-3-Yl)-4-Hydroxybut-3-En-2-One
CAS No.	728019-09-8
Molecular Formula	C9H8BrNO2
Molecular Weight	242.07 g/mol
Synonyms	4-(5-Bromo-3-pyridinyl)-4-hydroxy-3-buten-2-one; 4-Hydroxy-4-(5-bromopyridin-3-yl)but-3-en-2-one; 3-Buten-2-one, 4-(5-bromo-3-pyridinyl)-4-hydroxy-; (E)-4-(5-Bromopyridin-3-yl)-4-hydroxybut-3-en-2-one; 4-(5-Bromopyridin-3-yl)-4-oxobut-2-en-2-ol (tautomer)
EINECS	Contact for details

Quality Control

Our 4-(5-Bromopyridin-3-Yl)-4-Hydroxybut-3-En-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.