Description

6-Methoxy-2-Trifluoromethyl-3-Nitropyridine is a high-value, multi-functional heterocyclic building block characterized by its methoxy, trifluoromethyl, and nitro substituents. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl and nitro groups.
• Material Science Precursor: Serves as a building block for functionalized ligands, dyes, and advanced organic materials.
• Chemical Synthesis: Utilized in cross-coupling reactions, nucleophilic aromatic substitutions, and reduction reactions to create diverse pyridine derivatives.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	6-Methoxy-2-Trifluoromethyl-3-Nitropyridine
CAS No.	727993-33-1
Molecular Formula	C7H5F3N2O3
Molecular Weight	222.12 g/mol
Synonyms	3-Nitro-6-methoxy-2-(trifluoromethyl)pyridine; 2-Trifluoromethyl-6-methoxy-3-nitropyridine; 6-Methoxy-2-(trifluoromethyl)-3-nitropyridine; 6-Methoxy-2-trifluoromethyl-3-nitropyridine; 727993-33-1; Pyridine, 6-methoxy-2-(trifluoromethyl)-3-nitro-
EINECS	Contact for details

Quality Control

Our 6-Methoxy-2-Trifluoromethyl-3-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.