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6-Bromo-2-(4-Fluoro-Phenyl)-3-Piperazin-1-Ylmethyl-Imidazo[1,2-A]Pyridine CAS NO 727977-41-5


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CAS No.:727977-41-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Bromo-2-(4-Fluoro-Phenyl)-3-Piperazin-1-Ylmethyl-Imidazo[1,2-A]Pyridine is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. Its complex molecular architecture, featuring fused imidazopyridine, piperazine, and halogenated aryl rings, makes it a critical precursor for the synthesis of novel bioactive compounds. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and oncology targets.

Application

  • Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly for neurological and psychiatric disorders.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
  • Chemical Biology Probe Synthesis: Serves as a core scaffold for creating molecular probes to study biological pathways and protein functions.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
  • Academic Research: Utilized in university and institutional labs for heterocyclic chemistry studies and the development of new synthetic methodologies.

Basic Information

Product Name 6-Bromo-2-(4-Fluoro-Phenyl)-3-Piperazin-1-Ylmethyl-Imidazo[1,2-A]Pyridine
CAS No. 727977-41-5
Molecular Formula C18H18BrFN4
Molecular Weight 389.27 g/mol
Synonyms 6-Bromo-2-(4-fluorophenyl)-3-(piperazin-1-ylmethyl)imidazo[1,2-a]pyridine; 727977-41-5; Imidazo[1,2-a]pyridine, 6-bromo-2-(4-fluorophenyl)-3-(1-piperazinylmethyl)-; 3-(Piperazin-1-ylmethyl)-6-bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridine; 6-Bromo-2-(4-fluorophenyl)-3-(piperazin-1-ylmethyl)-imidazo[1,2-a]pyridine; 6-Bromo-2-(p-fluorophenyl)-3-(piperazin-1-ylmethyl)imidazo[1,2-a]pyridine
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Quality Control

Our 6-Bromo-2-(4-Fluoro-Phenyl)-3-Piperazin-1-Ylmethyl-Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our commitment to cGMP principles and rigorous quality control ensures a reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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