Description

6-Bromo-3-Hydroxypyridine-2-Carbonitrile is a versatile and high-value brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise functionalization for the development of novel active compounds. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, ligand synthesis, and the creation of complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its halogenated pyridine core.
• Ligand & Catalyst Development: Serves as a starting material for constructing complex chelating ligands used in catalysis and material science.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers due to its functional group diversity.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-Bromo-3-Hydroxypyridine-2-Carbonitrile
CAS No.	727737-00-0
Molecular Formula	C6H3BrN2O
Molecular Weight	199.01 g/mol
Synonyms	2-Cyano-6-bromo-3-hydroxypyridine; 3-Hydroxy-6-bromopyridine-2-carbonitrile; 6-Bromo-3-pyridinol-2-carbonitrile; 6-Bromo-2-cyano-3-pyridinol; 2-Pyridinecarbonitrile, 6-bromo-3-hydroxy-; 727737-00-0
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-3-Hydroxypyridine-2-Carbonitrile is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.