Description

6-Chloro-3-Hydroxypicolinonitrile is a versatile and high-value heterocyclic building block, specifically a substituted picolinonitrile derivative. Its unique molecular structure, featuring both chloro and hydroxyl substituents on the pyridine ring, makes it a critical intermediate for synthesizing complex molecules. This compound is essential for R&D and production in the pharmaceutical and agrochemical sectors, where it serves as a precursor for active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with targeted activity.
• Chemical Research & Development: Used in academic and industrial labs for exploring new heterocyclic chemistry and creating specialized ligand libraries.
• Material Science: Intermediate for the production of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis: Serves as a starting point for contract research organizations (CROs) and CDMOs to manufacture bespoke compounds for clients.

Basic Information

Product Name	6-Chloro-3-Hydroxypicolinonitrile
CAS No.	727736-70-1
Molecular Formula	C6H3ClN2O
Molecular Weight	154.55 g/mol
Synonyms	6-Chloro-3-hydroxypyridine-2-carbonitrile; 3-Hydroxy-6-chloropicolinonitrile; 2-Cyano-6-chloropyridin-3-ol; 6-Chloro-3-pyridinol-2-carbonitrile; 6-Chloro-3-hydroxypicolinic acid nitrile
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Hydroxypicolinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates, from early-stage research to scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.