Description

Methyl 6-Cyano-5-Hydroxypicolinate is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its unique pyridine core functionalized with ester, cyano, and hydroxyl groups, enabling its use in constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Serves as a versatile building block for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific functionalized picolinate derivatives.

Basic Information

Product Name	Methyl 6-Cyano-5-Hydroxypicolinate
CAS No.	727736-63-2
Molecular Formula	C8H6N2O3
Molecular Weight	178.15 g/mol
Synonyms	Methyl 5-hydroxy-6-cyanopyridine-2-carboxylate; 6-Cyano-5-hydroxypicolinic acid methyl ester; 2-Pyridinecarboxylic acid, 6-cyano-5-hydroxy-, methyl ester; 5-Hydroxy-6-cyano-2-pyridinecarboxylic acid methyl ester; Methyl 5-hydroxy-6-cyanopicolinate; 727736-63-2; Methyl 6-cyano-5-hydroxypyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 6-Cyano-5-Hydroxypicolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.