Description

3-(8-Methyl-2-p-Tolyl-Imidazo[1,2-A]Pyridin-3-Yl)-Acrylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique imidazopyridine-acrylic acid hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules targeting specific therapeutic pathways. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in oncology and CNS (Central Nervous System) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic frameworks via its reactive acrylic acid moiety.
• Bioconjugation & Probe Development: Potential use in developing fluorescent probes or affinity labels for biochemical assays due to its conjugated system.
• Material Science Research: Investigated as a monomer or component for specialty polymers with specific optical or electronic properties.

Basic Information

Product Name	3-(8-Methyl-2-p-Tolyl-Imidazo[1,2-A]Pyridin-3-Yl)-Acrylic Acid
CAS No.	727652-39-3
Molecular Formula	C20H18N2O2
Molecular Weight	318.37 g/mol
Synonyms	(E)-3-(8-Methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)acrylic acid; 3-(8-Methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl)-2-propenoic acid; 2-Propenoic acid, 3-(8-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl)-, (E)-; Imidazo[1,2-a]pyridine-3-acrylic acid, 8-methyl-2-(4-methylphenyl)-; 727652-39-3; 3-(8-Methyl-2-p-tolylimidazo[1,2-a]pyridin-3-yl)acrylic acid
EINECS	Contact for details

Quality Control

Our 3-(8-Methyl-2-p-Tolyl-Imidazo[1,2-A]Pyridin-3-Yl)-Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.