Description

3-[2-(4-Methoxy-Phenyl)-8-Methyl-Imidazo[1,2-A]-Pyridin-3-Yl]-Acrylic Acid is a specialized, high-purity organic compound belonging to the imidazopyridine class, serving as a critical advanced intermediate in pharmaceutical research and development. Its unique molecular structure, featuring an acrylic acid moiety, makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs) with targeted therapeutic properties. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new drug candidates and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, neurology, and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Active Pharmaceutical Ingredient (API) Development: Serves as an intermediate in the multi-step synthesis of complex target molecules for clinical trials.
• Agrochemical Research: Potential intermediate for developing new crop protection agents and pesticides due to its heterocyclic structure.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Biochemical Probe Development: Can be utilized to create tool compounds for investigating biological pathways and target validation.

Basic Information

Product Name	3-[2-(4-Methoxy-Phenyl)-8-Methyl-Imidazo[1,2-A]-Pyridin-3-Yl]-Acrylic Acid
CAS No.	727652-34-8
Molecular Formula	C18H16N2O3
Molecular Weight	308.33 g/mol
Synonyms	3-[2-(4-Methoxyphenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]acrylic acid; (E)-3-[2-(4-Methoxyphenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]acrylic acid; 2-(4-Methoxyphenyl)-8-methyl-3-(2-propenoyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-3-acrylic acid derivative; CAS 727652-34-8
EINECS	Contact for details

Quality Control

Our 3-[2-(4-Methoxy-Phenyl)-8-Methyl-Imidazo[1,2-A]-Pyridin-3-Yl]-Acrylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.