Description

3-[7-Methyl-2-(3-Nitro-Phenyl)-Imidazo[1,2-A]-Pyridin-3-Yl]-Acrylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique imidazopyridine-acrylic acid hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel small-molecule drug candidates targeting various therapeutic areas. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates in preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile chemical scaffold.
• API Development: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), especially in oncology and CNS therapeutic areas.
• Biochemical Tool Compound: Utilized in biochemical assays and as a probe to study specific biological pathways and enzyme interactions.
• Custom Synthesis: Starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client-specific research projects.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	3-[7-Methyl-2-(3-Nitro-Phenyl)-Imidazo[1,2-A]-Pyridin-3-Yl]-Acrylic Acid
CAS No.	727652-25-7
Molecular Formula	C₁₇H₁₃N₃O₄
Molecular Weight	323.30 g/mol
Synonyms	2-(3-Nitrophenyl)-7-methylimidazo[1,2-a]pyridine-3-acrylic acid; (E)-3-(7-Methyl-2-(3-nitrophenyl)imidazo[1,2-a]pyridin-3-yl)acrylic acid; 3-(7-Methyl-2-(3-nitrophenyl)imidazo[1,2-a]pyridin-3-yl)-2-propenoic acid; Imidazo[1,2-a]pyridine-3-acrylic acid, 7-methyl-2-(3-nitrophenyl)-; 727652-25-7; 3-(7-Methyl-2-(3-nitrophenyl)imidazo[1,2-a]pyridin-3-yl)acrylic acid
EINECS	Contact for details

Quality Control

Our 3-[7-Methyl-2-(3-Nitro-Phenyl)-Imidazo[1,2-A]-Pyridin-3-Yl]-Acrylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.