Description

6-Bromo-2-(3-Nitro-Phenyl)-Imidazo[1,2-A]Pyridine-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its imidazopyridine core functionalized with bromo, nitro-phenyl, and aldehyde groups. This compound matters as a critical building block in medicinal chemistry, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of small-molecule therapeutics, particularly for oncology and central nervous system disorders.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile reactive sites.
• Chemical Biology Probes: Employed in the development of chemical probes to study biological pathways and protein functions.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to construct complex heterocyclic frameworks for material science applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	6-Bromo-2-(3-Nitro-Phenyl)-Imidazo[1,2-A]Pyridine-3-Carbaldehyde
CAS No.	727652-11-1
Molecular Formula	C14H8BrN3O3
Molecular Weight	346.14 g/mol
Synonyms	6-Bromo-2-(3-nitrophenyl)imidazo[1,2-a]pyridine-3-carboxaldehyde; 6-Bromo-2-(3-nitrophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde; Imidazo[1,2-a]pyridine-3-carbaldehyde, 6-bromo-2-(3-nitrophenyl)-; 727652-11-1; 6-Bromo-2-(3-nitro-phenyl)-imidazo[1,2-a]pyridine-3-carbaldehyde; 2-(3-Nitrophenyl)-6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(3-Nitro-Phenyl)-Imidazo[1,2-A]Pyridine-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specified parameters. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.