Description

4-Chloro-3-Methyl-5-Phenylpyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its versatile halogenated pyridine core, which serves as a key intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting neurological and oncological diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine structure.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Acts as a scaffold for designing molecular probes and inhibitors to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Chloro-3-Methyl-5-Phenylpyridine
CAS No.	727429-31-4
Molecular Formula	C12H10ClN
Molecular Weight	203.67 g/mol
Synonyms	4-Chloro-3-methyl-5-phenylpyridine; 5-Phenyl-4-chloro-3-methylpyridine; 3-Methyl-5-phenyl-4-chloropyridine; 4-Chloro-3-methyl-5-phenyl-pyridine; Pyridine, 4-chloro-3-methyl-5-phenyl-
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Methyl-5-Phenylpyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) are available for every batch and supplied upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.