Description

3-Oxabicyclo[3.2.0]Heptane-2-Carboxylicacid,Methylester,(1S,2S,5R)-(9Ci) is a high-purity, chiral bicyclic lactone derivative that serves as a critical synthetic intermediate. Its defined stereochemistry and unique oxabicyclo[3.2.0]heptane scaffold make it an invaluable building block for constructing complex, biologically active molecules. This compound is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of prostaglandins, prostacyclin analogs, and other bioactive molecules with complex ring systems.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in stereoselective reactions to introduce specific chiral centers into target compounds.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new chemical entities (NCEs), particularly for targets requiring constrained, oxygen-containing bicyclic frameworks.
• Fine Chemical Production: Serves as a specialized starting material for the custom synthesis of high-value, low-volume chemicals for advanced applications.
• Process Chemistry Development: Used in route scouting and scale-up studies for the efficient production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-Oxabicyclo[3.2.0]Heptane-2-Carboxylicacid,Methylester,(1S,2S,5R)-(9Ci)
CAS No.	727428-91-3
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(1S,2S,5R)-Methyl 3-oxabicyclo[3.2.0]heptane-2-carboxylate; (1S,2S,5R)-3-Oxabicyclo[3.2.0]heptane-2-carboxylic Acid Methyl Ester; Methyl (1S,2S,5R)-3-oxabicyclo[3.2.0]heptane-2-carboxylate; (1S,2S,5R)-rel-Methyl 3-oxabicyclo[3.2.0]heptane-2-carboxylate; Chiral Bicyclic Lactone Ester; Prostaglandin Intermediate
EINECS	Contact for details

Quality Control

Our 3-Oxabicyclo[3.2.0]Heptane-2-Carboxylicacid,Methylester,(1S,2S,5R)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be sensitive to moisture and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.