Description

4-(6-Chloropyridine-3-Carbonyl)Benzoic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine and benzoate ester structure. This compound is of significant commercial value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, leveraging its chloropyridine moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors and functional polymers due to its conjugated aromatic system.
• Custom Synthesis and Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.
• Academic and Industrial R&D: Utilized in research laboratories for methodological studies and exploring new chemical reactions.

Basic Information

Product Name	4-(6-Chloropyridine-3-Carbonyl)Benzoic Acid Ethyl Ester
CAS No.	727409-20-3
Molecular Formula	C15H12ClNO3
Molecular Weight	289.71 g/mol
Synonyms	Ethyl 4-[(6-chloropyridin-3-yl)carbonyl]benzoate; 4-[(6-Chloro-3-pyridinyl)carbonyl]benzoic Acid Ethyl Ester; Benzoic acid, 4-[(6-chloro-3-pyridinyl)carbonyl]-, ethyl ester; Ethyl 4-(6-chloronicotinoyl)benzoate; 727409-20-3; 4-(6-Chloronicotinoyl)benzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 4-(6-Chloropyridine-3-Carbonyl)Benzoic Acid Ethyl Ester is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (HPLC), with higher purities available upon request. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.