Description

Methyl 4-Iodo-2-Methoxypyridine-3-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, where the iodine and ester functional groups serve as key handles for cross-coupling reactions and further derivatization. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in drug discovery and material science programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core structure.
• Material Science: Serves as a building block for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki-Miyaura, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Biology: Utilized in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	Methyl 4-Iodo-2-Methoxypyridine-3-Carboxylate
CAS No.	726206-56-0
Molecular Formula	C8H8INO3
Molecular Weight	293.06 g/mol
Synonyms	Methyl 4-iodo-2-methoxynicotinate; 3-Pyridinecarboxylic acid, 4-iodo-2-methoxy-, methyl ester; 4-Iodo-2-methoxypyridine-3-carboxylic acid methyl ester; 2-Methoxy-4-iodonicotinic acid methyl ester; Methyl 4-iodo-2-methoxypyridine-3-carboxylate; 726206-56-0; Methyl 4-iodo-2-methoxynicotinate
EINECS	Contact for details

Quality Control

Our Methyl 4-Iodo-2-Methoxypyridine-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.