Description

4-Iodo-2-Oxo-1,2-Dihydropyridine-3-Carbaldehyde is a high-value, halogenated heterocyclic building block with significant synthetic utility. This compound is prized for its role as a versatile intermediate in the construction of complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive aldehyde and halogen functionalities.
• Material Science: Serves as a building block for organic electronic materials, ligands for catalysis, and specialty polymers.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl and other conjugated systems.
• Medicinal Chemistry Library Synthesis: Employed in high-throughput and combinatorial chemistry to generate diverse libraries of pyridine-based compounds for biological screening.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological processes and target engagement.

Basic Information

Item	Detail
Product Name	4-Iodo-2-Oxo-1,2-Dihydropyridine-3-Carbaldehyde
CAS No.	726206-53-7
Molecular Formula	C6H4INO2
Molecular Weight	248.99 g/mol
Synonyms	4-Iodo-2-oxo-1,2-dihydropyridine-3-carboxaldehyde; 3-Formyl-4-iodo-2(1H)-pyridinone; 4-Iodo-3-formyl-2(1H)-pyridone; 4-Iodo-2-hydroxynicotinaldehyde; 4-Iodopyridone-3-carbaldehyde; 4-Iodo-1H-pyridin-2-one-3-carbaldehyde; 3-Aldehyde-4-iodo-2-pyridone
EINECS	Contact for details

Quality Control

Our 4-Iodo-2-Oxo-1,2-Dihydropyridine-3-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept away from direct light sources. For long-term storage, consider storing under an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.