Description

1,4-Dioxaspiro[4.5]Decane-2-Propanol,(2S)-(9Ci) is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its unique spirocyclic structure and defined stereochemistry make it a critical precursor for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral catalysts, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the preparation of specialty chemicals, advanced ligands, and complex natural product analogs.
• Catalyst and Ligand Development: Serves as a precursor for novel chiral catalysts and auxiliaries used in enantioselective transformations.
• Agrochemical Research: Employed in the development of new, stereochemically defined active ingredients for crop protection.
• Material Science: A building block for creating specialized polymers and advanced organic materials with tailored properties.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and stereochemistry research.

Basic Information

Product Name	1,4-Dioxaspiro[4.5]Decane-2-Propanol,(2S)-(9Ci)
CAS No.	726193-04-0
Molecular Formula	C11H20O3
Molecular Weight	200.27 g/mol
Synonyms	(2S)-1,4-Dioxaspiro[4.5]decane-2-propanol; (S)-1,4-Dioxaspiro[4.5]decane-2-propanol; (2S)-2-(2-Hydroxyethyl)-1,4-dioxaspiro[4.5]decane; (S)-2-(2-Hydroxyethyl)-1,4-dioxaspiro[4.5]decane; (S)-1,4-Dioxaspiro[4.5]decan-2-ethanol; (2S)-1,4-Dioxaspiro[4.5]decan-2-ethanol; Spirocyclic chiral diol derivative; Chiral spiroketal alcohol
EINECS	Contact for details

Quality Control

Our production of 1,4-Dioxaspiro[4.5]Decane-2-Propanol,(2S)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to verify identity, enantiomeric excess, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. Our quality system is designed to support cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.