Description

1,4-Piperidinedicarboxylic Acid, 4-Methyl-, 1-(1,1-Dimethylethyl) 4-Methyl Ester is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry and functional group manipulation are required.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the piperidine scaffold for biological activity.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes, enzyme inhibitors, and other tools for biochemical research.
• Asymmetric Synthesis: Utilized as a chiral building block or auxiliary in stereoselective reactions to create enantiomerically pure compounds.
• Ligand & Catalyst Development: Acts as a foundational structure for creating novel ligands used in catalytic processes, including metal-catalyzed cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules at various scales.

Basic Information

Product Name	1,4-Piperidinedicarboxylic Acid, 4-Methyl-, 1-(1,1-Dimethylethyl) 4-Methyl Ester
CAS No.	724790-59-4
Molecular Formula	C14H25NO4
Molecular Weight	271.35 g/mol
Synonyms	tert-Butyl 4-Methyl-4-(methoxycarbonyl)piperidine-1-carboxylate; 1-Boc-4-Methyl-4-piperidinecarboxylic Acid Methyl Ester; 1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylic Acid Methyl Ester; Methyl 1-Boc-4-methylpiperidine-4-carboxylate; 4-Methyl-1,4-piperidinedicarboxylic Acid 1-tert-Butyl Ester 4-Methyl Ester; 4-Methyl-1-Boc-piperidine-4-carboxylic Acid Methyl Ester; 1-N-Boc-4-methylisonipecotic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 1,4-Piperidinedicarboxylic Acid, 4-Methyl-, 1-(1,1-Dimethylethyl) 4-Methyl Ester adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our facilities and processes are designed to meet the exacting standards required for pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.