Description

Ethynylestradiol Sulfate is a sulfate ester derivative of the synthetic estrogen, ethinyl estradiol. This compound is a key pharmaceutical intermediate of significant importance in the development and manufacturing of advanced hormonal therapies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of steroidal drugs, particularly for applications in hormone replacement therapy and contraceptive formulations.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of steroidal active pharmaceutical ingredients (APIs).
• Hormone Replacement Therapy (HRT) Research: Used in the development of novel estrogen-based treatments for menopausal symptoms.
• Contraceptive Formulation Development: Serves as a precursor in the research and production of next-generation oral contraceptives.
• Biochemical Research: Employed in studies investigating estrogen metabolism, receptor binding, and sulfate conjugation pathways.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for complex steroidal molecules.

Basic Information

Product Name	Ethynylestradiol Sulfate
CAS No.	724762-79-2
Molecular Formula	C20H24O5S
Molecular Weight	376.47 g/mol
Synonyms	Ethinyl Estradiol Sulfate; 17α-Ethynylestradiol 3-Sulfate; EE2 Sulfate; 19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol 3-Sulfate; Ethynylestradiol 3-Sulfate; 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-Sulfate
EINECS	Contact for details

Quality Control

Our Ethynylestradiol Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.