Description

Spiro[Benzofuran-3(2H),4'-Piperidine], 6-(Trifluoromethyl)- is a high-value, complex heterocyclic compound featuring a unique spirocyclic architecture. This structure is of significant interest in advanced organic synthesis, particularly for constructing novel molecular scaffolds with tailored properties. It serves as a critical pharmaceutical intermediate and a versatile building block for research in medicinal chemistry and material science. Industries engaged in the development of new active pharmaceutical ingredients (APIs) and specialty fine chemicals are the primary users of this sophisticated compound.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in the development of complex molecules for agrochemicals, dyes, and advanced materials due to its rigid spirocyclic core.
• Chemical Biology Probe: Serves as a molecular tool for investigating biological pathways and protein-ligand interactions in academic and industrial R&D.

Basic Information

Product Name	Spiro[Benzofuran-3(2H),4'-Piperidine], 6-(Trifluoromethyl)-
CAS No.	721958-57-2
Molecular Formula	C14H14F3NO
Molecular Weight	269.26 g/mol
Synonyms	6-(Trifluoromethyl)spiro[benzofuran-3(2H),4'-piperidine]; 6-(Trifluoromethyl)-2,3-dihydro-1-benzofuran-3-spiro-4'-piperidine; 6-Trifluoromethylspiro[benzofuran-3(2H),4'-piperidine]; 721958-57-2; Spiro[1-benzofuran-3(2H),4'-piperidine], 6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2,3-dihydrospiro[benzofuran-3,4'-piperidine]
EINECS	Contact for details

Quality Control

Our Spiro[Benzofuran-3(2H),4'-Piperidine], 6-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from techniques such as HPLC, NMR, and GC-MS. Our quality commitment ensures the material meets the stringent requirements for use in pharmaceutical development and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.