Description

12-Azidododecylphosphonic Acid, 95% is a specialized bifunctional organophosphorus compound featuring a long alkyl chain terminated with a reactive azide group. This unique structure makes it a valuable surface modification agent and click chemistry precursor, enabling the covalent attachment of molecules to various substrates. It is primarily utilized by researchers and manufacturers in the fields of materials science, nanotechnology, and bioconjugation for creating functionalized surfaces and advanced polymer networks.

Application

• Surface Functionalization: Used to create self-assembled monolayers (SAMs) on metal oxides (e.g., titanium, aluminum, stainless steel) for corrosion inhibition, lubrication, or to provide a reactive handle for further grafting.
• Click Chemistry Substrate: The terminal azide group participates in copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC) reactions, enabling efficient "click" coupling with alkyne-bearing molecules.
• Polymer Modification: Incorporated as a comonomer or post-polymerization modifier to introduce phosphonic acid and azide functionalities into polymers, enhancing adhesion to inorganic surfaces or enabling cross-linking.
• Biomaterial Engineering: Facilitates the immobilization of biomolecules (peptides, proteins, carbohydrates) onto implant surfaces or diagnostic platforms to improve biocompatibility and specificity.
• Lubricant and Anti-wear Additive: The phosphonic acid head group provides strong chemisorption to metal surfaces, forming protective layers that reduce friction and wear.
• Nanoparticle Capping Agent: Stabilizes metal oxide nanoparticles and provides a route for their functionalization via the azide group for catalytic or sensing applications.

Basic Information

Product Name	12-Azidododecylphosphonic Acid, 95%
CAS No.	721457-32-5
Molecular Formula	C₁₂H₂₆N₃O₃P
Molecular Weight	291.33 g/mol
Synonyms	12-Azidododecylphosphonic Acid; Dodecylphosphonic Acid Azide; ω-Azidododecylphosphonic Acid; 12-Azido-1-dodecylphosphonic Acid; Azido-PEG11-phosphonic Acid (approximate); N3-C12-PA; Phosphonic acid, P-(12-azidododecyl)-; Azido-terminated phosphonic acid
EINECS	Contact for details

Quality Control

Our 12-Azidododecylphosphonic Acid, 95% is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity (HPLC), identity (NMR, IR), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.