Description

3-Pyridinemethanamine,N,n-Diethyl--α-,-α--Difluoro-(9Ci) is a specialized fluorinated pyridine derivative that serves as a high-value building block in advanced organic synthesis. This compound is particularly significant for its role in introducing the difluoromethylamine moiety into complex molecular architectures, a key modification for tuning the physicochemical and biological properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, central nervous system (CNS) agents, and other small-molecule therapeutics where the difluoroethylamino group is desired.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where fluorination enhances metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials that require specific fluorine and nitrogen motifs.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	3-Pyridinemethanamine,N,n-Diethyl--α-,-α--Difluoro-(9Ci)
CAS No.	721451-43-0
Molecular Formula	C10H14F2N2
Molecular Weight	200.23 g/mol
Synonyms	N,N-Diethyl-α,α-difluoro-3-pyridinemethanamine; 3-[(Diethylamino)difluoromethyl]pyridine; α,α-Difluoro-3-pyridinemethanamine, N,N-diethyl-; 3-Pyridinemethanamine, N,N-diethyl-α,α-difluoro-; (Diethylamino)difluoro(pyridin-3-yl)methane; 721451-43-0; (3-Pyridyl)difluoromethyl-diethylamine
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinemethanamine,N,n-Diethyl--α-,-α--Difluoro-(9Ci) is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents. Due to its fluoride/strong alkali nature, ensure containers are kept tightly sealed to prevent moisture ingress or degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.