Description

L-Serine, n-(2-Methylpropylidene)-, [N(E)]- (9Ci) CAS NO 720703-29-7 is a specialized derivative of the amino acid L-serine, featuring an isobutylidene protecting group on the amine functionality. This compound is a critical chiral building block and intermediate in advanced organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical development teams for applications in medicinal chemistry, peptide synthesis, and the production of high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic pathways.
• Peptide Chemistry: Used in the synthesis of modified peptides and peptidomimetics, where the protected amine group allows for selective reactions and the introduction of specific side-chain functionalities.
• Asymmetric Synthesis: Acts as a precursor or auxiliary in catalytic asymmetric reactions to create enantiomerically pure compounds for agrochemicals and specialty materials.
• Biochemical Research: Employed in studies of enzyme mechanisms, metabolic pathways, and as a standard or reagent in analytical method development.
• Fine Chemical Production: Integral to the multi-step synthesis of complex natural products, flavors, fragrances, and advanced material precursors.

Basic Information

Product Name	L-Serine, n-(2-Methylpropylidene)-, [N(E)]- (9Ci)
CAS No.	720703-29-7
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(2S)-2-Amino-3-hydroxypropanoic acid N-(2-methylpropylidene) derivative; N-Isobutylidene-L-serine; L-Serine, N-(2-methylpropylidene)-; (S)-2-(2-Methylpropylideneamino)-3-hydroxypropanoic acid; [N(E)]-L-Serine n-(2-methylpropylidene)-; (9CI) 720703-29-7; Serine isobutylidene derivative
EINECS	Contact for details

Quality Control

Our production of L-Serine, n-(2-Methylpropylidene)-, [N(E)]- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our clients with detailed Certificates of Analysis (COA), which include data from chiral HPLC, NMR, and mass spectrometry. Our quality systems are designed to meet the rigorous standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption, which could affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.