Description

2-Chloro-6-Fluorophenyl Isocyanate is a versatile and highly reactive aromatic isocyanate building block, essential for the synthesis of advanced chemical intermediates. Its core value lies in introducing the isocyanate functional group into molecular scaffolds, enabling the formation of ureas, carbamates, and other heterocyclic compounds critical for material science and pharmaceutical development. This compound is primarily needed by R&D chemists and process engineers in the agrochemical and pharmaceutical industries for creating novel active ingredients and functional polymers.

Application

• Agrochemical Intermediate: Key precursor in the synthesis of modern herbicides, fungicides, and insecticides, where the chloro-fluoro-phenyl moiety contributes to biological activity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry to construct urea-based pharmacophores and active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes, coatings, and adhesives with enhanced performance characteristics.
• Chemical Research & Development: A fundamental reagent for exploring new synthetic pathways and developing novel heterocyclic compounds in academic and industrial laboratories.
• Dye & Pigment Synthesis: Employed in the manufacture of advanced colorants and functional dyes where specific halogenated aromatic structures are required.

Basic Information

Product Name	2-Chloro-6-Fluorophenyl Isocyanate
CAS No.	720678-21-7
Molecular Formula	C7H3ClFNO
Molecular Weight	171.56 g/mol
Synonyms	1-Chloro-2-fluoro-6-isocyanatobenzene; 2-Fluoro-6-chlorophenyl isocyanate; (2-Chloro-6-fluorophenyl)isocyanate; Isocyanic acid, 2-chloro-6-fluorophenyl ester; 2-Chloro-6-fluoro-1-isocyanatobenzene; 2-Chloro-6-fluorobenzene isocyanate
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluorophenyl Isocyanate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under a dry inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as alcohols, amines, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.