Description

2-(tert-Butoxycarbonyl)-2-Methylpropanoic Acid is a high-purity, protected carboxylic acid derivative widely used as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile intermediate for introducing the tert-butoxycarbonyl (Boc) protected carboxylic acid moiety, which is essential for constructing complex molecules with precise stereochemistry and functionality. This compound is particularly vital for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of active pharmaceutical ingredients (APIs), peptides, and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry.
• Peptide Synthesis: Used in the preparation of Boc-protected amino acid derivatives for solid-phase and solution-phase peptide synthesis.
• Agrochemical Production: Serves as an intermediate in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed as a versatile reagent for introducing protected carboxylic acid groups in multi-step synthetic routes for fine chemicals.
• Material Science Research: Utilized in the development of novel polymers, dendrimers, and functional materials requiring specific acid-protection strategies.
• Chemical Biology & Proteomics: Acts as a tool compound for labeling and modifying biomolecules in research applications.

Basic Information

Product Name	2-(tert-Butoxycarbonyl)-2-Methylpropanoic Acid
CAS No.	718632-38-3
Molecular Formula	C9H16O4
Molecular Weight	188.22 g/mol
Synonyms	2-(Boc)-2-Methylpropanoic Acid; 2-(tert-Butoxycarbonyl)-2-Methylpropionic Acid; 2-Methyl-2-[(2-methylpropan-2-yl)oxycarbonyl]propanoic Acid; Boc-Pivalic Acid; (Boc)2CCOOH; tert-Butyl 2-Carboxy-2-methylpropanoate; 2-(tert-Butoxycarbonyl)isobutyric Acid; 2-(Boc)-Isobutyric Acid
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxycarbonyl)-2-Methylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.