Description

2-Bromo-1-(4-Chloropyridin-2-Yl)Ethanone is a high-purity halogenated pyridinyl ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key electrophilic intermediate, enabling the introduction of functionalized acetyl moieties into complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with pyridine-based scaffolds.
• Chemical Biology Probe Development: Serves as a reactive handle for labeling proteins or creating activity-based probes for target identification.
• Material Science Research: Employed in the synthesis of functionalized ligands for catalysts or metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring this precise molecular fragment.

Basic Information

Product Name	2-Bromo-1-(4-Chloropyridin-2-Yl)Ethanone
CAS No.	718595-36-9
Molecular Formula	C7H5BrClNO
Molecular Weight	234.48 g/mol
Synonyms	2-Bromo-1-(4-chloro-2-pyridinyl)ethanone; 1-(4-Chloro-2-pyridinyl)-2-bromoethanone; 2-Bromo-1-(4-chloropyridin-2-yl)ethan-1-one; Ethanone, 2-bromo-1-(4-chloro-2-pyridinyl)-; 718595-36-9; 4-Chloro-2-(bromoacetyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4-Chloropyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.